Eugenie Bergogne-berezin

Acinetobacter: Biology and Pathogenesis - Infectious Agents and Pathogenesis Eugenie Bergogne-berezin Softcover reprint of hardcover 1st ed. 2008 edition

Marc Notes: Includes bibliographical references and index. Table of Contents: Introduction and Perspectives Eugenie Bergogne-Berezin -- 1. Importance of Acinetobacter spp / Eugenie Bergogne-Berezin -- 2. Overview of the Microbial Characteristics, Taxonomy, and Epidemiology of Acinetobacter / Harald Seifert, Lenie Dijkshoorn -- 3. Genome Organization, Mutation, and Gene Expression in Acinetobacter / L. Nicholas Organston, Donna Parke -- 4. Molecular Epidemiology of Acinetobacter Species / Hilmar Wisplinghoff, Harald Seifert -- 5. Typing Acinetobacter Strains: Applications and Methods / Lenie Dijkshoorn -- 6. Efflux Pumps in Acinetobacter baumannii / Thamarai Schneiders, Jacqueline Findlay, Sebastian G. B. Amyes -- 7. Acinetobacter baumannii: Mechanisms of Resistance, Multiple ?-Lactamases / Laurent Poirel, Patrice Nordmann -- 8. Virulence Mechanisms of Acinetobacter / Grziela Braun -- 9. Nosocomial and Community-acquired Acinetobacter Infections / Marie Laure Joly-Guillou -- 10. Experimental Models of Acinetobacter Infection / Marie Laure Joly-Guillou, Michel Wolff -- 11. Antimicrobial Resistance and Therapeutic Alternatives / Jordi Vila, Jeronimo Pachon -- 12. US Army Experience with Acinetobacter in Operation Iraqi Freedom / Clinton Murray, Paul T. Scott, Kim A. Moran, David W. Craft -- 13. Perspectives / Eugenie Bergogne-Berezin -- Subject Index. Publisher Marketing: There is currently increasing interest concerning the biology and disease caused by Acinetobacter species. Such interest, however, developed relatively slowly because of the necessity to clarify the confusing taxonomy of these organisms. Much work was needed to identify various species as members of this genus, to recognize their epidemiologic profile, their pathogenic role and their increasing importance as multi-antibiotic resistant organisms. In recent years improvement of genetic approaches, recognition of plasmids, integrons and chromosomal sources of resistance mechanisms aroused interest on the role of Acinetobacters in disease by many microbiologists and clinicians, especially internists and infectious disease specialists. In this regard, physicians are frequently confronted with extremely difficult therapeutic approaches for treatment and prevention of severe nosocomial infections due to multi antibiotic resistant Acinetobacter. Moreover, recent observations of community acquired infections have been reported, especially in patients with various risk factors such as immuno-deficiencies. Also, it is now becoming evident that Acinetobacter infections occur frequently in violent situations such as earthquake or war zones. The mechanisms of Acinetobacter virulence are becoming increasingly clear, providing new insights into their pathogenic role in community acquired infections. It is apparent the time is appropriate for detailed review of the increasing knowledge concerning important new information, both clinical and therapeutic, especially information concerning virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are accumulating in almostan exponential manner since publication of previous books on this subject in 1991 and 1996.

Contributor Bio:  Friedman, Herman Friedman is Chairman and Distinguished Professor of Microbiology and Immunology at the University of South Florida College of Medicine.