Sofien Kamoun

Therapies Delivered by Automatic Implantable Defibrillators Sofien Kamoun

Appropriate effective therapy is the essential goal of the implantable automatic defibrillator. The occurrence of inappropriate therapy is a potentially serious event. Methods: We conducted a study that included 80 patients implanted with ICDs in the cardiology department of Habib Thameur Hospital in Tunis between January 2010 and June 2019. Results: The median age of the patients was 58 years (52.25-65.75) with a sex ratio of 12.1H/F. During a median follow-up of 48 months, 695 therapies were recorded: 62% anti-tachycardia pacing (ATP) and 38% shocks with a predominance of appropriate therapies (87.8%). The incidence of therapies was 4.72 therapies/patient-year at 1 year, 3.28 therapies/patient-year at 3 years and 0.78 therapies/patient-year at 5 years. In multivariate analysis, the independent predictors of death were inappropriate therapy (RR = 1.102 with a 95% CI of (1.026-1.184), p=0.008), ischemic heart disease (RR = 2.965 with a 95% CI of (0.931-9.444), p=0.066), and LVEF less than 29% (RR = 2.340 with a 95% CI of (0.942-5.809), p=0.067