Godfred Epie Essongolle

Modeling Rejection Immunity: a Proposed Model Godfred Epie Essongolle

In this Book we consider the problem of modeling the dynamics of the Immune system during and after a solid organ transplantation, taking into consideration the pharmacodynamics of different therapeutic drugs Immunosupressants like "Cyclosporine" and "Thymoglobulin" at different doses during the Grafts lifespan which affect the dynamics of the Cellular and Humoral pathways of the Immune systems. The proposed model extends the Gaetano et al.'s model considering both the Cellular and Humoral Pathways. Some preliminary results of a numerical simulation are given proving that the model behaves as predicted by physical tacticians.