Thomas G Davies

Fragment-Based Drug Discovery and X-Ray Crystallography - Topics in Current Chemistry Thomas G Davies 2012 edition

Jacket Description/Back: D. A. Erlanson Introduction to Fragment-Based Drug Discovery T. G. Davies Ian J. Tickle Fragment Screening Using X-Ray Crystallography S. Roughley L. Wright P. Brough A. Massey R. E. Hubbard Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening D. F. Wyss Y.-S. Wang H. L. Eaton C. Strickland J.s H. Voigt Z. Zhu A. W. Stamford Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors M. Hennig A. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery E. Valkov T. Sharpe M. Marsh Sa. Greive M. Hyvonen Targeting Protein Protein Interactions and Fragment-Based Drug Discovery J.h D. Bauman D. Patel E. Arnold Fragment Screening and HIV Therapeutics D. Rognan Fragment-Based Approaches and Computer-Aided Drug Discovery"Table of Contents: Introduction to Fragment-Based Drug Discovery / Daniel A. Erlanson -- Fragment Screening Using X-Ray Crystallography / Thomas G. Davies, Ian J. Tickle -- Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening / Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey, Roderick E. Hubbard -- Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 inhibitors / Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaning Zhu, Andrew W. Stamford -- Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery / Michael Henning, Armin Ruf, Walter Huber -- Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery / Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive, Marko HyvOnen -- Fragment Screening and HIV Therapeutics / Joseph D. Bauman, Disha Patel, Eddy Arnold -- Fragment-Based Approaches and Computer-Aided Drug Discovery / Didier Rognan -- Index.