Modelling and Optimization of Biotechnological Processes: Artificial Intelligence Approaches - Studies in Computational Intelligence - Lei Zhi Chen - Libros - Springer-Verlag Berlin and Heidelberg Gm - 9783642067921 - 18 de noviembre de 2010
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Lei Zhi Chen
Modelling and Optimization of Biotechnological Processes: Artificial Intelligence Approaches - Studies in Computational Intelligence 1st Ed. Softcover of Orig. Ed. 2006 edition

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Mostindustrialbiotechnologicalprocessesareoperatedempirically. Oneofthe major di?culties of applying advanced control theories is the highly nonlinear nature of the processes. This book examines approaches based on arti?cial intelligencemethods,inparticular,geneticalgorithmsandneuralnetworks,for monitoring, modelling and optimization of fed-batch fermentation processes. The main aim of a process control is to maximize the ?nal product with minimum development and production costs. This book is interdisciplinary in nature, combining topics from biotechn- ogy, arti?cial intelligence, system identi?cation, process monitoring, process modelling and optimal control. Both simulation and experimental validation are performed in this study to demonstrate the suitability and feasibility of proposed methodologies. An online biomass sensor is constructed using a - current neural network for predicting the biomass concentration online with only three measurements (dissolved oxygen, volume and feed rate). Results show that the proposed sensor is comparable or even superior to other sensors proposed in the literature that use more than three measurements. Biote- nological processes are modelled by cascading two recurrent neural networks. It is found that neural models are able to describe the processes with high accuracy. Optimization of the ?nal product is achieved using modi?ed genetic algorithms to determine optimal feed rate pro?les. Experimental results of the corresponding production yields demonstrate that genetic algorithms are powerful tools for optimization of highly nonlinear systems. Moreover, a c- bination of recurrentneural networks and genetic algorithms provides a useful and cost-e?ective methodology for optimizing biotechnological processes.

123 pages, 11 black & white tables, biography

Medios de comunicación Libros     Paperback Book   (Libro con tapa blanda y lomo encolado)
Publicado 18 de noviembre de 2010
ISBN13 9783642067921
Editores Springer-Verlag Berlin and Heidelberg Gm
Páginas 123
Dimensiones 156 × 234 × 7 mm   ·   195 g
Lengua Inglés  

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