Alexzander Asea

Heat Shock Protein-Based Therapies - Heat Shock Proteins Alexzander Asea 1st ed. 2015 edition

Jacket Description/Back: The book "Heat Shock Protein-Based Therapies" provides the most up-to-date review on new heat shock protein-based mechanisms used in the therapy and treatment of various human disorders and diseases, including cancer, muscular atrophy, neurodegenerative disorders (Alzheimer's Disease, Multiple Sclerosis) and infectious diseases (HIV, periodontal disease). Written by leaders in the field of heat shock protein research, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which mechanisms dependent on heat shock proteins are targeted. The chapters also provide answers as to HSP biological significance to the host. This book is a must read for graduate and postgraduates in the field of Drug Development, Biotechnology, Pharmaceutical Industry, Phytomedicine, Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Oncology, Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology."Table of Contents: Contents ContributorsPreface SECTION I: HEAT SHOCK PROTEIN HSP27-BASED THERAPIES1 HSP27 as a Therapeutic Target of Novel Inhibitors and Dietary Phytochemicals in CancerElena Arechaga-Ocampo and Cesar Lopez-Camarillo2 Heat Shock Protein 27 (HSP27, HSPB1) is Up-Regulated by Targeted Agents and Confers Resistance to Both Targeted Drugs and ChemotherapeuticsDaniele Musiani, John D. Konda, Simona Pavan, Erica Torchiaro, Jessica Erriquez, Martina Olivero and Maria F. Di Renzo 3 Heat Shock Proteins and Cancer: Plant Based TherapyEvren Onay-Ucar SECTION II: HEAT SHOCK PROTEIN HSP60-BASED THERAPIES4 Chaperonotherapy for Alzheimer s Disease: Focusing on HSP60Francesco Cappello, Antonella M. Gammazza, Silvia Vilasi, Maria G. Ortore, Pier L. San-Biagio, Claudia Campanella, Andrea Pace, Antonio P. Piccionello, Giulio Taglialatela, Everly C. De Macario and Alberto J. l. Macario 5 Secreted and Circulating Cell Stress Proteins in the Periodontal DiseasesBrian Henderson, Nikos Donos, Luigi Nibali and Frank Kaiser SECTION III: HEAT SHOCK PROTEIN HSP70-BASED THERAPIES 6 The Role of Heat Shock Protein 70 in Infection and Immunity Jose Rey-Ladino, Abiola Senok, Abdullah Sarkar and Ahlam Al Shedoukhy 7 Potential Cytoprotective Effects of Heat Shock Proteins to Skeletal Muscle John P. Vardiman, Philip M. Gallagher and Jacob A. Siedlik 8 Heat Shock Proteins in Triple-Negative Breast Cancer (TNBC) TreatmentPunit Kaurunit Kaur, Tarundeep arundeep Singh, Moses Galukandealukande, Sunil Krishnanrishnan and Alexzander A. A. Asealexzander Asea 9 Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe? Rosaria Tinnirello, Giuseppina Turturici, Gabriella Sconzo, Walter Spinello, Alexzander A. A. Asea and Fabiana Geraci 10 New Indications for HSP90 and HSP70 Inhibitors as Antiviral Drugs Matthew K. Howe and Timothy A. J. Haystead 11 Potential Applications of Nanoparticles for Hyperthermia Caio C. Quini and Sunil Krishnan SECTION IV: HEAT SHOCK PROTEIN HSP90-BASED THERAPIES 12 Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer TreatmentSusanta S. Adhikari, Sujan K. Mondal and Rajkumar Banerjee 13 Potential of HSP90 Inhibitors to Treat Neurofibromatosis-Related TumorsJeremie Vitte and Marco Giovannini 14 Role of Heat Shock Protein 90 in the Cause of Various Diseases: A Potential Therapeutic TargetSubhankar Paul 15 HSP90 Inhibitor-Based Strategies for Cancer Therapy: Advancing Toward Clinical ImpactDavid A. Proia and Richard C. Bates 16 Molecular Survival Strategies of Organisms: HSP and Small Molecules for Diagnostics and Drug DevelopmentAndreas Kirschning, Johanna-Gabriela Walter, Frank Stahl, Emilia Schax, Thomas Scheper, Pooyan Aliuos and Carsten Zeilinger17 Targeting Heat Shock Proteins in Colorectal CancerSheah L. Lee, Nina C. Dempsey-Hibbert, Dale Vimalachandran, Terence D. Wardle, Paul Sutton and John H. H. Williams Index"