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Dynamics and Kinetics in Structural Biology: Unravelling Function Through Time-Resolved Structural Analysis Moffat, Keith (The University of Chicago, Chicago, IL, USA) 1.º edición
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Dynamics and Kinetics in Structural Biology: Unravelling Function Through Time-Resolved Structural Analysis
Moffat, Keith (The University of Chicago, Chicago, IL, USA)
This book aims to promote and encourage the rapid and successful development of dynamics and kinetics in structural biology. It is easy to propose dynamic experiments; it is much harder to design good experiments that will carefully address specific questions, execute the experiments effectively, analyze the data thoroughly and interpret the results thoughtfully. This book will address all these aspects, providing a sound understanding of the tools and helping readers to identify problems that are still outstanding in this fast-moving area. The advantages and limitations of X-ray techniques are presented, and the book explores both parallel techniques such as ultrafast optical studies and computation, and related structural techniques such as cryoelectron microscopy and nuclear magnetic resonance.
The book is divided into eight chapters; chapters one and two provide a robust introduction to the principles of kinetics and dynamics as well as the physical chemistry of reactions. Chapter three takes an in-depth look at the experimental process, including initiating the reaction, signal and noise, the sample, time-resolved crystallography and solution scattering. Chapter four covers x-ray sources, beamlines and detectors, while chapter five covers data analysis and interpretation. Chapters six and seven discuss other structural biology techniques and experimental examples. The book concludes with a chapter discussing future directions including new sources and overcoming experimental limitations.
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288 pages
| Medios de comunicación | Libros Hardcover Book (Libro con lomo y cubierta duros) |
| Publicado | 6 de noviembre de 2023 |
| ISBN13 | 9781119696285 |
| Editores | John Wiley & Sons Inc |
| Páginas | 288 |
| Dimensiones | 251 × 175 × 20 mm · 644 g |
| Lengua | Inglés |
