Precision Crystallization: Theory and Practice of Controlling Crystal Size - Ingo Leubner - Libros - Taylor & Francis Ltd - 9780367385163 - 19 de septiembre de 2019
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Precision Crystallization: Theory and Practice of Controlling Crystal Size 1.º edición

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Despite the fact that crystals make up an estimated 80% of chemical and pharmaceutical products, few resources exist that provide practical guidance on achieving precision control of their size and size distribution. Based on a model developed by the author and his colleagues, Precision Crystallization: Theory and Practice of Controlling Crystal Size presents scientists and product engineers with the tools to control crystal nucleation, enabling them to ultimately control crystal size and size distribution for batch and continuous crystallizations.





At the cutting edge of crystallization science and technology, this volume presents information never before available. Introducing the Balanced Nucleation and Growth (BNG) model, the book demonstrates how the results of the nucleation process are quantitatively related to practical experimental control values such as:









reaction addition rate



crystal solubility

temperature

residence time (continuous crystallizations)

the effect of ripening agents (crystal supersizing) during nucleation

the effect of crystal growth restrainers (crystal nanosizing) during nucleation

control of renucleation





The author shows how the BNG theory predicts previously unknown phenomena and also how it corrects erroneous perceptions of the importance of reaction volume on the outcome of crystal nucleation. Going above and beyond classical nucleation theories which rely to a large extent on guesswork, the BNG model gives precise guidance to scientists working in a range of critical areas, leading to promising implications for research, quality control, product development, production processes, pilot plant operations, and manufacturing.


216 pages

Medios de comunicación Libros     Paperback Book   (Libro con tapa blanda y lomo encolado)
Publicado 19 de septiembre de 2019
ISBN13 9780367385163
Editores Taylor & Francis Ltd
Páginas 216
Dimensiones 234 × 156 × 12 mm   ·   350 g
Lengua Inglés  

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